WERAM Information

Tag Content
WERAM ID WERAM-Art-0053
Ensembl Protein ID AT2G35160.1
Uniprot Accession O82175; SUVH5_ARATH
Genbank Protein ID NP_181061.1
Protein Name Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5
Genbank Nucleotide ID NM_129070.2
Gene Name SUVH5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G35160 AT2G35160.1 AT2G35160.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SUV39 SET H3K9 K 22549957; 20703330
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SUV39 2.80e-42 145 648 764
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
Domain Profile
  HMT SUV39
    SUV39.txt   2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladld 56 
                  +L++fkte++GwGvr+l++i+ gsF+c+yaGe+l+d++ae+   + +deyl+dl 
  AT2G35160.1 648 KLEIFKTESRGWGVRSLESIPIGSFICEYAGELLEDKQAESL--TGKDEYLFDLG 700
                  8**************************************977..999*****986 PP
    SUV39.txt  88 eeseyiidakkegnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150
                  e++ ++i+a+++gn+grf+nHscspNl+ q v++d+++ r+p+++fFa ++i++ +EL++dY+
  AT2G35160.1 702 EDDPFTINAAQKGNIGRFINHSCSPNLYAQDVLYDHEEIRIPHIMFFALDNIPPLQELSYDYN 764
                  6789**********************************************************7 PP
Protein Sequence
(Fasta)		MVHSESSILS SLRGGDGGGI PCSKDELAIN GSYTDPMGRR KSKRFKVAAE SEFSPDFGSI 60
TRQLRSRRMQ KEFTVETYET RNVSDVCVLS SQADVELIPG EIVAERDSFK SVDCNDMSVG 120
LTEGAESLGV NMQEPMKDRN MPENTSEQNM VEVHPPSISL PEEDMMGSVC RKSITGTKEL 180
HGRTISVGRD LSPNMGSKFS KNGKTAKRSI SVEEENLVLE KSDSGDHLGP SPEVLELEKS 240
EVWIITDKGV VMPSPVKPSE KRNGDYGEGS MRKNSERVAL DKKRLASKFR LSNGGLPSCS 300
SSGDSARYKV KETMRLFHET CKKIMQEEEA RPRKRDGGNF KVVCEASKIL KSKGKNLYSG 360
TQIIGTVPGV EVGDEFQYRM ELNLLGIHRP SQSGIDYMKD DGGELVATSI VSSGGYNDVL 420
DNSDVLIYTG QGGNVGKKKN NEPPKDQQLV TGNLALKNSI NKKNPVRVIR GIKNTTLQSS 480
VVAKNYVYDG LYLVEEYWEE TGSHGKLVFK FKLRRIPGQP ELPWKEVAKS KKSEFRDGLC 540
NVDITEGKET LPICAVNNLD DEKPPPFIYT AKMIYPDWCR PIPPKSCGCT NGCSKSKNCA 600
CIVKNGGKIP YYDGAIVEIK PLVYECGPHC KCPPSCNMRV SQHGIKIKLE IFKTESRGWG 660
VRSLESIPIG SFICEYAGEL LEDKQAESLT GKDEYLFDLG DEDDPFTINA AQKGNIGRFI 720
NHSCSPNLYA QDVLYDHEEI RIPHIMFFAL DNIPPLQELS YDYNYKIDQV YDSNGNIKKK 780
FCYCGSAECS GRLY 794
Nucleotide Sequence
(Fasta)		AGGAATTGAA GAAGTTATAG AGCCAGAGCC AAAGATGCAT GCTAGGACTC TGTTCATAAG 60
AATTATTTTT GTTTTGCAGG ACAATGCCAA ATTAACCCAA TTTGAGTAGG CGACTCACAT 120
ATCTCCCGCT CCGGCCAATC GACTCGTCAT CTCCGCCATT ATCACTACTC CTTCCTTCAT 180
TTCTGGCGTT GGGCATCATG GTACATTCAG AGTCATCAAT ACTTAGTTCC TTGCGCGGTG 240
GTGATGGCGG TGGTATTCCT TGTTCTAAGG ATGAACTAGC AATAAATGGT AGTTACACCG 300
ATCCTATGGG GCGGAGGAAG TCCAAGCGGT TTAAGGTTGC TGCGGAAAGT GAGTTTTCAC 360
CTGATTTTGG ATCGATTACC AGGCAGCTCA GATCGAGAAG AATGCAGAAG GAGTTCACAG 420
TTGAGACTTA CGAGACCAGG AATGTTTCTG ATGTTTGTGT TCTCTCTTCT CAAGCTGATG 480
TTGAGTTGAT TCCTGGAGAA ATTGTTGCAG AAAGAGATAG CTTTAAGTCG GTTGATTGTA 540
ATGACATGTC GGTTGGGTTA ACCGAAGGAG CTGAATCTCT TGGAGTTAAC ATGCAAGAAC 600
CTATGAAAGA TAGGAATATG CCAGAGAACA CAAGTGAGCA AAATATGGTG GAGGTCCATC 660
CTCCAAGCAT AAGCCTGCCA GAGGAAGATA TGATGGGGTC TGTTTGCAGG AAAAGCATCA 720
CTGGAACAAA GGAGCTTCAC GGAAGAACGA TCTCTGTTGG GAGAGACTTA TCTCCAAATA 780
TGGGGAGCAA GTTTTCAAAG AATGGAAAGA CCGCTAAACG TTCTATATCG GTGGAAGAGG 840
AAAACTTGGT TCTGGAGAAG TCAGATTCTG GAGACCATTT GGGTCCATCA CCAGAGGTTT 900
TGGAACTTGA GAAATCAGAG GTTTGGATAA TTACAGACAA AGGGGTTGTA ATGCCTTCAC 960
CAGTGAAGCC TTCCGAGAAG AGGAATGGAG ATTATGGTGA AGGATCTATG AGGAAGAATA 1020
GTGAGAGGGT TGCCCTGGAT AAAAAGAGAT TAGCTAGTAA ATTTCGGTTA TCAAATGGTG 1080
GGCTTCCTAG TTGCTCAAGC AGTGGGGATA GTGCTCGGTA TAAAGTTAAG GAAACAATGC 1140
GTCTTTTCCA TGAAACTTGT AAAAAAATTA TGCAAGAGGA AGAAGCAAGG CCTAGGAAAA 1200
GAGATGGTGG CAATTTCAAA GTGGTTTGCG AGGCTTCGAA AATTCTCAAG AGTAAAGGGA 1260
AAAATCTTTA TAGTGGTACT CAGATTATTG GAACTGTGCC TGGTGTTGAG GTTGGCGATG 1320
AATTTCAATA TAGAATGGAG CTGAACCTTC TTGGTATACA TAGACCAAGT CAAAGTGGTA 1380
TCGACTATAT GAAAGATGAC GGTGGGGAAC TAGTTGCCAC GAGTATTGTA TCCTCGGGAG 1440
GTTATAATGA CGTGCTTGAT AACTCTGATG TCTTGATCTA CACGGGTCAA GGCGGAAATG 1500
TGGGGAAAAA GAAAAATAAT GAACCACCCA AAGACCAGCA GCTTGTAACG GGAAACCTTG 1560
CGTTGAAAAA CAGTATAAAC AAAAAGAACC CTGTGCGGGT CATAAGAGGC ATCAAAAATA 1620
CGACATTACA ATCATCAGTT GTTGCAAAGA ATTATGTTTA CGATGGATTG TATCTGGTGG 1680
AAGAGTACTG GGAAGAAACC GGGTCTCACG GTAAACTCGT CTTCAAGTTC AAACTACGGC 1740
GTATTCCTGG ACAACCCGAG CTTCCCTGGA AAGAGGTTGC GAAATCGAAA AAATCTGAGT 1800
TCCGGGATGG TCTTTGCAAT GTTGATATCA CAGAAGGGAA AGAGACATTA CCCATATGCG 1860
CTGTGAACAA TTTAGACGAT GAGAAACCGC CACCGTTTAT CTACACGGCT AAAATGATAT 1920
ATCCGGATTG GTGCCGGCCA ATTCCTCCAA AGAGCTGCGG TTGCACAAAC GGCTGCTCCA 1980
AGTCAAAAAA CTGTGCCTGC ATTGTGAAAA ACGGTGGAAA GATACCTTAT TACGATGGAG 2040
CCATTGTTGA AATTAAGCCC CTGGTCTATG AGTGTGGCCC ACACTGCAAA TGCCCACCTT 2100
CTTGCAACAT GAGAGTCTCA CAGCACGGGA TCAAGATCAA GCTGGAGATC TTCAAAACGG 2160
AGTCAAGAGG TTGGGGAGTG AGATCGCTGG AATCTATTCC TATCGGGAGC TTCATCTGTG 2220
AGTACGCAGG AGAGCTTCTA GAGGATAAAC AAGCTGAAAG CCTTACCGGG AAAGATGAGT 2280
ATCTTTTTGA TCTCGGGGAC GAGGATGATC CGTTCACCAT AAACGCAGCA CAGAAAGGGA 2340
ACATAGGGAG GTTTATAAAC CATAGCTGCT CGCCGAATCT GTACGCACAG GACGTATTGT 2400
ACGACCATGA GGAAATAAGA ATACCTCACA TTATGTTCTT TGCACTGGAC AATATACCTC 2460
CACTTCAGGA ACTCTCGTAC GACTACAATT ATAAGATCGA TCAGGTATAC GACTCTAATG 2520
GTAATATCAA GAAGAAATTT TGCTATTGTG GTTCCGCTGA GTGTAGTGGT AGGCTCTACT 2580
AATAAGCTGT TGTTAGCACT TGTATTCTTC TTCATTTTCC CCCTTGATGT TCAGTTCTGT 2640
CTGAATAAGC AAATTAGAAG ACAGCTTTAG CCAAATTTTC AACACATTGT ATGACATAAT 2700
TGGTGTCAAT TAGTGTTGTC ATGTTTTAGC TGCATTGTTT CATTATTATG TTATTCACTG 2760
AACCTCACCA TAATCCAAGT ATTTCATAGT TATTTTCA 2799
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0137--Centromere
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
--
Interpro

IPR025794--Hist-Lys_N-MeTrfase_plant
IPR003616--Post-SET_dom
IPR007728--Pre-SET_dom
IPR015947--PUA-like_domain
IPR001214--SET_dom
IPR003105--SRA_YDG
PROSITE

PS50868--POST_SET
PS50867--PRE_SET
PS51575--SAM_MT43_SUVAR39_2
PS50280--SET
PS51015--YDG
Pfam

PF05033--Pre-SET
PF02182--SAD_SRA
PF00856--SET
Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0005634--C:nucleus
GO:0042054--F:histone methyltransferase activity
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0031048--P:chromatin silencing by small RNA
GO:0016571--P:histone methylation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0010200--P:response to chitin
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0129 scaffold_402114.1 Arabidopsis lyrata 84 0.0 1310
WERAM-Bro-0067 Bo4g038960.1 Brassica oleracea 58 0.0 738
WERAM-Brr-0150 Bra030212.1-P Brassica rapa 63 0.0 682
WERAM-Prp-0019 EMJ11616 Prunus persica 64 0.0 665
WERAM-Viv-0003 VIT_00s0309g00020.t01 Vitis vinifera 63 0.0 663
WERAM-Pot-0036 POPTR_0003s08130.1 Populus trichocarpa 63 0.0 661
WERAM-Sol-0078 Solyc06g060960.1.1 Solanum lycopersicum 62 0.0 649
WERAM-Thc-0040 EOY24196 Theobroma cacao 62 0.0 644
WERAM-Sot-0083 PGSC0003DMT400068350 Solanum tuberosum 62 0.0 637
WERAM-Met-0121 AES94344 Medicago truncatula 61 1e-179 627
WERAM-Glm-0122 GLYMA11G04071.1 Glycine max 60 2e-174 610
WERAM-Amt-0001 ERN01091 Amborella trichopoda 56 1e-167 587
WERAM-Brd-0107 BRADI4G28792.1 Brachypodium distachyon 53 4e-150 529
WERAM-Orbr-0107 OB09G14850.1 Oryza brachyantha 51 6e-149 525
WERAM-Sob-0027 Sb02g022936.1 Sorghum bicolor 53 4e-145 513
WERAM-Zem-0104 GRMZM2G300955_P01 Zea mays 53 1e-144 511
WERAM-Sei-0101 Si028728m Setaria italica 53 2e-144 511
WERAM-Orm-0092 OMERI09G05880.1 Oryza meridionalis 52 3e-144 509
WERAM-Orgl-0098 OGLUM09G07810.1 Oryza glumaepatula 51 2e-142 503
WERAM-Ori-0109 BGIOSGA030599-PA Oryza indica 51 4e-142 503
WERAM-Orl-0090 KN540051.1_FGP003 Oryza longistaminata 51 6e-142 502
WERAM-Tra-0019 Traes_1BS_0FB6F2DA6.3 Triticum aestivum 50 2e-141 500
WERAM-Lep-0098 LPERR09G05040.1 Leersia perrieri 51 3e-141 499
WERAM-Orr-0105 ORUFI09G07880.1 Oryza rufipogon 50 1e-140 498
WERAM-Orp-0095 OPUNC09G06250.1 Oryza punctata 52 3e-140 496
WERAM-Hov-0016 MLOC_14516.1 Hordeum vulgare 50 3e-140 496
WERAM-Ors-0090 OS09T0362900-01 Oryza sativa 50 3e-140 496
WERAM-Aet-0032 EMT23957 Aegilops tauschii 50 4e-140 496
WERAM-Tru-0080 TRIUR3_29767-P1 Triticum urartu 50 4e-139 493
WERAM-Orb-0102 OBART09G07450.1 Oryza barthii 50 4e-139 493
WERAM-Org-0097 ORGLA09G0054000.1 Oryza glaberrima 50 1e-138 491
WERAM-Orni-0091 ONIVA08G14800.1 Oryza nivara 49 8e-133 472
WERAM-Sem-0004 EFJ22703 Selaginella moellendorffii 46 4e-115 413
WERAM-Php-0129 PP1S9_150V6.1 Physcomitrella patens 43 5e-98 356
Created Date 25-Jun-2016