WERAM Information

Tag Content
WERAM ID WERAM-Art-0041
Ensembl Protein ID AT2G22740.2
Uniprot Accession Q8VZ17; SUVH6_ARATH; Q9C5P2; Q9ZQ40
Genbank Protein ID NP_850030.1; NP_973514.1
Protein Name Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6
Genbank Nucleotide ID NM_179699.2; NM_201785.1
Gene Name SUVH6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G22740 AT2G22740.2 AT2G22740.2
AT2G22740 AT2G22740.1 AT2G22740.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SUV39 SET H3K9 K 22549957; 20703330
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SUV39 5.30e-49 166.8 617 760
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression. Seems to act preferentially on dsMRNA.
Domain Profile
  HMT SUV39
    SUV39.txt   2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladldskesvenlkegyesdvplssdssntrqekdkeeseyiidakke 99 
                  +L++fkt+++GwGvrcl++i+ gsF+c+y+Ge+l+d+eae++    +deyl+d+ + ++  n   + +s++ l+++   ++  + +e+s ++ida+++
  AT2G22740.2 617 PLEIFKTKSRGWGVRCLKSIPIGSFICEYVGELLEDSEAERR--IGNDEYLFDIGNRYD--NSLAQGMSELMLGTQAG-RSMAEGDESSGFTIDAASK 709
                  69***************************************9..8899*******9876..56666777777776665.5556666999********* PP
    SUV39.txt 100 gnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150
                  gnvgrf+nHscspNl+ qnv++d++d+r+p+v+fFa+++i++ +EL++dY+
  AT2G22740.2 710 GNVGRFINHSCSPNLYAQNVLYDHEDSRIPHVMFFAQDNIPPLQELCYDYN 760
                  **************************************************7 PP
Protein Sequence
(Fasta)		MEMGVMENLM VHTEISKVKS QSNGEVEKRG VSVLENGGVC KLDRMSGLKF KRRKVFAVRD 60
FPPGCGSRAM EVKIACENGN VVEDVKVVES LVKEEESLGQ RDASENVSDI RMAEPVEVQP 120
LRICLPGGDV VRDLSVTAGD ECSNSEQIVA GSGVSSSSGT ENIVRDIVVY ADESSLGMDN 180
LDQTQPLEIE MSDVAVAKPR LVAGRKKAKK GIACHSSLKV VSREFGEGSR KKKSKKNLYW 240
RDRESLDSPE QLRILGVGTS SGSSSGDSSR NKVKETLRLF HGVCRKILQE DEAKPEDQRR 300
KGKGLRIDFE ASTILKRNGK FLNSGVHILG EVPGVEVGDE FQYRMELNIL GIHKPSQAGI 360
DYMKYGKAKV ATSIVASGGY DDHLDNSDVL TYTGQGGNVM QVKKKGEELK EPEDQKLITG 420
NLALATSIEK QTPVRVIRGK HKSTHDKSKG GNYVYDGLYL VEKYWQQVGS HGMNVFKFQL 480
RRIPGQPELS WVEVKKSKSK YREGLCKLDI SEGKEQSPIS AVNEIDDEKP PLFTYTVKLI 540
YPDWCRPVPP KSCCCTTRCT EAEARVCACV EKNGGEIPYN FDGAIVGAKP TIYECGPLCK 600
CPSSCYLRVT QHGIKLPLEI FKTKSRGWGV RCLKSIPIGS FICEYVGELL EDSEAERRIG 660
NDEYLFDIGN RYDNSLAQGM SELMLGTQAG RSMAEGDESS GFTIDAASKG NVGRFINHSC 720
SPNLYAQNVL YDHEDSRIPH VMFFAQDNIP PLQELCYDYN YALDQVRDSK GNIKQKPCFC 780
GAAVCRRRLY
Nucleotide Sequence
(Fasta)		AAAAAATTCG ACTATATTTA TAACTTTGGC GAAATCTCAA ATTTCCGATT ACTACCAAAT 60
TCGATTCCTT CATCTTCTTC TCCACCATTT TTCGATCGCA GACGAAGATC TTTCACCGAT 120
TGTGAATGGA AATGGGAGTT ATGGAGAATT TGATGGTACA TACGGAGATA TCAAAGGTTA 180
AGTCTCAGAG CAATGGTGAG GTGGAGAAAC GAGGAGTGTC AGTTTTGGAG AATGGTGGTG 240
TTTGCAAGCT TGATCGAATG AGTGGGCTTA AGTTTAAGCG TCGGAAGGTT TTTGCTGTGA 300
GGGACTTTCC ACCGGGTTGT GGTTCGAGAG CAATGGAAGT GAAGATTGCT TGTGAGAATG 360
GGAATGTTGT TGAAGATGTT AAGGTTGTTG AGTCTTTGGT TAAAGAGGAG GAGAGTTTGG 420
GGCAGAGAGA TGCCTCTGAA AACGTGAGTG ATATCAGAAT GGCTGAGCCG GTGGAGGTTC 480
AGCCTCTGAG AATTTGTTTG CCAGGAGGTG ATGTGGTAAG AGACTTGTCT GTTACCGCGG 540
GAGACGAGTG TTCAAACAGT GAACAGATTG TGGCGGGTTC TGGTGTTAGC AGCAGCAGCG 600
GAACTGAAAA CATTGTCAGG GATATCGTTG TTTACGCAGA TGAGAGCAGT CTAGGAATGG 660
ATAATTTGGA TCAAACTCAG CCGCTAGAAA TTGAAATGTC AGATGTTGCA GTTGCAAAAC 720
CGAGGCTTGT TGCGGGTAGA AAGAAGGCAA AGAAAGGAAT TGCATGTCAT TCATCCTTGA 780
AGGTTGTTAG CCGAGAGTTT GGTGAAGGAT CTAGGAAGAA GAAGAGTAAG AAGAATTTAT 840
ATTGGCGTGA TAGGGAAAGT CTGGATTCTC CTGAGCAGCT TCGGATACTA GGTGTTGGGA 900
CAAGCAGCGG TTCAAGCAGC GGTGATAGTA GTCGGAACAA AGTAAAGGAA ACTCTACGTC 960
TTTTCCATGG CGTTTGCAGA AAGATTCTGC AGGAGGATGA AGCAAAGCCT GAGGACCAAA 1020
GGAGAAAAGG TAAAGGTCTT AGAATAGATT TTGAGGCTTC GACCATTCTC AAAAGGAATG 1080
GCAAATTTCT CAACTCTGGT GTGCATATTT TGGGAGAAGT GCCTGGGGTT GAGGTTGGTG 1140
ATGAGTTCCA ATATAGGATG GAGCTGAACA TTCTTGGTAT ACATAAACCA AGCCAGGCCG 1200
GTATCGATTA TATGAAATAT GGTAAGGCCA AAGTTGCGAC AAGTATTGTA GCCTCTGGAG 1260
GGTATGACGA CCATCTGGAT AACTCGGATG TCTTGACCTA CACTGGTCAA GGCGGAAACG 1320
TGATGCAAGT AAAGAAGAAG GGAGAGGAAC TGAAAGAGCC TGAAGACCAA AAGCTTATTA 1380
CCGGAAACCT CGCGTTAGCA ACCAGCATAG AAAAACAAAC CCCTGTGCGT GTCATTAGAG 1440
GCAAACATAA GTCAACTCAT GATAAATCAA AAGGTGGAAA TTATGTTTAC GACGGATTAT 1500
ATCTTGTGGA AAAGTATTGG CAACAAGTCG GATCTCACGG TATGAATGTC TTCAAGTTTC 1560
AACTTAGGCG CATACCTGGA CAACCTGAAC TTTCTTGGGT AGAGGTGAAG AAATCTAAGT 1620
CAAAATACCG GGAAGGTCTA TGCAAGCTTG ACATCTCAGA AGGGAAAGAG CAGTCACCCA 1680
TTAGCGCTGT GAACGAAATA GACGACGAGA AACCGCCTTT GTTCACCTAC ACTGTTAAAC 1740
TGATTTACCC AGATTGGTGC AGACCAGTTC CTCCAAAGTC ATGCTGTTGC ACCACGCGCT 1800
GCACCGAAGC TGAAGCGAGG GTGTGCGCTT GTGTGGAGAA AAACGGTGGA GAGATACCGT 1860
ACAACTTCGA TGGAGCCATT GTTGGTGCAA AACCTACTAT CTATGAATGT GGCCCACTCT 1920
GCAAATGCCC TTCTAGTTGC TACCTAAGAG TCACACAGCA TGGGATCAAG TTACCGCTTG 1980
AGATCTTCAA AACCAAGTCA AGAGGTTGGG GAGTGAGATG TCTTAAGTCG ATCCCTATTG 2040
GTAGCTTCAT ATGTGAATAC GTTGGTGAAC TTTTAGAGGA TAGTGAAGCA GAAAGAAGAA 2100
TCGGGAACGA CGAGTATCTC TTTGATATTG GTAACAGATA TGATAACTCT TTAGCTCAAG 2160
GGATGTCAGA GCTAATGCTG GGGACACAGG CAGGCCGATC TATGGCAGAA GGTGATGAGT 2220
CGAGTGGATT CACCATTGAT GCAGCAAGTA AGGGTAATGT TGGGAGGTTC ATAAACCATA 2280
GCTGCTCGCC AAATCTGTAC GCCCAAAACG TTTTGTATGA TCATGAAGAC TCTAGAATCC 2340
CTCACGTGAT GTTCTTCGCA CAGGACAATA TACCTCCGCT TCAAGAACTC TGTTACGACT 2400
ACAATTACGC GCTCGATCAG GTACGTGACT CTAAGGGTAA TATCAAGCAG AAACCTTGCT 2460
TTTGTGGTGC TGCCGTATGT AGGCGTAGGC TCTATTGATA GATGATTCGC CTCCAACTTT 2520
TATCTCTGTG TCATTATGAT TCTTTCTTGT TTTCATTTGT ATTTGTCACT ACACAAGTGT 2580
ATAATCAG 2589
Sequence Source Ensembl
Keyword

KW-0137--Centromere
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
--
Interpro

IPR025794--Hist-Lys_N-MeTrfase_plant
IPR003616--Post-SET_dom
IPR007728--Pre-SET_dom
IPR015947--PUA-like_domain
IPR001214--SET_dom
IPR003105--SRA_YDG
PROSITE

PS50868--POST_SET
PS50867--PRE_SET
PS51575--SAM_MT43_SUVAR39_2
PS50280--SET
PS51015--YDG
Pfam

PF05033--Pre-SET
PF02182--SAD_SRA
PF00856--SET
Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008327--F:methyl-CpG binding
GO:0010428--F:methyl-CpNpG binding
GO:0010429--F:methyl-CpNpN binding
GO:0008168--F:methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0016571--P:histone methylation
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0007 Al_scaffold_0004_216 Arabidopsis lyrata 79 0.0 1234
WERAM-Bro-0077 Bo4g150950.1 Brassica oleracea 69 0.0 763
WERAM-Brr-0150 Bra030212.1-P Brassica rapa 69 0.0 759
WERAM-Prp-0019 EMJ11616 Prunus persica 66 0.0 672
WERAM-Viv-0003 VIT_00s0309g00020.t01 Vitis vinifera 63 0.0 645
WERAM-Thc-0040 EOY24196 Theobroma cacao 63 0.0 643
WERAM-Pot-0036 POPTR_0003s08130.1 Populus trichocarpa 63 0.0 637
WERAM-Met-0121 AES94344 Medicago truncatula 63 0.0 634
WERAM-Sol-0078 Solyc06g060960.1.1 Solanum lycopersicum 61 2e-180 629
WERAM-Sot-0083 PGSC0003DMT400068350 Solanum tuberosum 61 6e-176 615
WERAM-Glm-0122 GLYMA11G04071.1 Glycine max 62 1e-174 611
WERAM-Amt-0001 ERN01091 Amborella trichopoda 57 1e-168 590
WERAM-Brd-0107 BRADI4G28792.1 Brachypodium distachyon 55 4e-151 533
WERAM-Orbr-0107 OB09G14850.1 Oryza brachyantha 52 2e-145 514
WERAM-Orm-0092 OMERI09G05880.1 Oryza meridionalis 53 5e-144 509
WERAM-Ori-0109 BGIOSGA030599-PA Oryza indica 52 8e-144 508
WERAM-Orgl-0098 OGLUM09G07810.1 Oryza glumaepatula 52 9e-144 508
WERAM-Orl-0090 KN540051.1_FGP003 Oryza longistaminata 52 2e-143 507
WERAM-Zem-0104 GRMZM2G300955_P01 Zea mays 54 5e-143 506
WERAM-Orr-0105 ORUFI09G07880.1 Oryza rufipogon 52 9e-143 504
WERAM-Ors-0090 OS09T0362900-01 Oryza sativa 52 1e-142 504
WERAM-Sei-0101 Si028728m Setaria italica 54 3e-142 503
WERAM-Orb-0102 OBART09G07450.1 Oryza barthii 52 4e-141 499
WERAM-Org-0097 ORGLA09G0054000.1 Oryza glaberrima 52 7e-141 498
WERAM-Lep-0098 LPERR09G05040.1 Leersia perrieri 52 2e-140 497
WERAM-Aet-0032 EMT23957 Aegilops tauschii 51 2e-139 493
WERAM-Tra-0034 Traes_1DS_5A7302FDE.1 Triticum aestivum 51 4e-139 493
WERAM-Hov-0016 MLOC_14516.1 Hordeum vulgare 51 1e-138 491
WERAM-Tru-0080 TRIUR3_29767-P1 Triticum urartu 50 9e-138 488
WERAM-Sob-0027 Sb02g022936.1 Sorghum bicolor 54 6e-137 485
WERAM-Orp-0095 OPUNC09G06250.1 Oryza punctata 51 7e-134 475
WERAM-Orni-0091 ONIVA08G14800.1 Oryza nivara 47 5e-131 466
WERAM-Sem-0004 EFJ22703 Selaginella moellendorffii 46 8e-112 402
WERAM-Php-0129 PP1S9_150V6.1 Physcomitrella patens 41 8e-101 365
Created Date 25-Jun-2016