WERAM Information

Tag Content
WERAM ID WERAM-Art-0027
Ensembl Protein ID AT1G73100.1
Uniprot Accession Q9C5P4; SUVH3_ARATH; Q9SSL7
Genbank Protein ID NP_565056.1
Protein Name Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH3
Genbank Nucleotide ID NM_105968.3
Gene Name SUVH3;SET19;SDG19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G73100 AT1G73100.1 AT1G73100.1
Details
Type Family Domain Substrates AA References (PMIDs)
HMT SUV39 SET H3K9 K 20703330; 15659850
Status Reviewed
Classification
Type Family E-value Score Start End
HMT SUV39 1.80e-45 155.4 495 638
Organism Arabidopsis thaliana
NCBI Taxa ID 3702
Functional Description
(View)		 Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
Domain Profile
  HMT SUV39
    SUV39.txt   2 rLqvfktenkGwGvrclddiakgsFvciyaGeiltddeaekegleegdeyladldskesv..enlkegyesdvplssdssntrqekdkeeseyiidak 97 
                  rL+vfkt+n+GwG+r++d++++gsF+c+yaGe+ ++ + + +  +e+d y++d++++ ++  +n++++ +++ p      ++  e+++  s ++i+ak
  AT1G73100.1 495 RLEVFKTRNRGWGLRSWDSLRAGSFICEYAGEVKDNGNLRGN--QEEDAYVFDTSRVFNSfkWNYEPELVDEDPS-----TEVPEEFNLPSPLLISAK 585
                  8********************************999998766..9*********998876567777777666655.....78888999********** PP
    SUV39.txt  98 kegnvgrflnHscspNlfvqnvfvdthdlrfprvafFaskrikagtELtwdYg 150
                  k gnv+rf+nHscspN+f+q+v+ + + + + ++afFa+++i+++ ELt+dYg
  AT1G73100.1 586 KFGNVARFMNHSCSPNVFWQPVIREGNGESVIHIAFFAMRHIPPMAELTYDYG 638
                  ****************************************************6 PP
Protein Sequence
(Fasta)		MQGVPGFNTV PNPNHYDKSI VLDIKPLRSL KPVFPNGNQG PPFVGCPPFG PSSSEYSSFF 60
PFGAQQPTHD TPDLNQTQNT PIPSFVPPLR SYRTPTKTNG PSSSSGTKRG VGRPKGTTSV 120
KKKEKKTVAN EPNLDVQVVK KFSSDFDSGI SAAEREDGNA YLVSSVLMRF DAVRRRLSQV 180
EFTKSATSKA AGTLMSNGVR TNMKKRVGTV PGIEVGDIFF SRIEMCLVGL HMQTMAGIDY 240
IISKAGSDEE SLATSIVSSG RYEGEAQDPE SLIYSGQGGN ADKNRQASDQ KLERGNLALE 300
NSLRKGNGVR VVRGEEDAAS KTGKIYIYDG LYSISESWVE KGKSGCNTFK YKLVRQPGQP 360
PAFGFWKSVQ KWKEGLTTRP GLILPDLTSG AESKPVSLVN DVDEDKGPAY FTYTSSLKYS 420
ETFKLTQPVI GCSCSGSCSP GNHNCSCIRK NDGDLPYLNG VILVSRRPVI YECGPTCPCH 480
ASCKNRVIQT GLKSRLEVFK TRNRGWGLRS WDSLRAGSFI CEYAGEVKDN GNLRGNQEED 540
AYVFDTSRVF NSFKWNYEPE LVDEDPSTEV PEEFNLPSPL LISAKKFGNV ARFMNHSCSP 600
NVFWQPVIRE GNGESVIHIA FFAMRHIPPM AELTYDYGIS PTSEARDESL LHGQRTCLCG 660
SEQCRGSFG 669
Nucleotide Sequence
(Fasta)		GAAAATGCTT TAATGAAAGG GCGTCTCTGT ACACGTAGCC ACTTGCTTCT TTCACTCTCT 60
CTCTCTCGTC AGGAATCGTC TCTGCTCTTT CATCATCCTC CGAGAATTAT CACACAAGGT 120
CACTGCAAGG TGTGTACGAG AGGGCTAAAG TAAATGGTGT TGTTGTGATA TTCATCTTAT 180
TTTTGACAGC TTGAAATAGA GGAGTTTAGC AATGCAAGGA GTTCCTGGAT TTAATACTGT 240
TCCAAATCCT AACCATTATG ACAAATCAAT AGTGTTAGAT ATTAAACCGT TGCGAAGTTT 300
GAAACCTGTT TTTCCAAATG GTAATCAAGG TCCACCTTTT GTTGGTTGTC CACCTTTTGG 360
TCCTTCCTCA TCTGAGTATT CTTCTTTCTT CCCATTTGGA GCACAACAAC CAACGCATGA 420
TACTCCAGAT CTCAACCAAA CTCAGAACAC GCCTATTCCA TCATTTGTTC CACCTCTTCG 480
ATCGTATAGA ACACCTACTA AAACAAATGG CCCCAGCAGC TCCAGTGGAA CTAAAAGAGG 540
TGTTGGTCGA CCTAAGGGAA CTACTAGTGT GAAGAAAAAA GAGAAGAAGA CTGTGGCCAA 600
TGAGCCTAAC TTAGATGTTC AGGTAGTGAA AAAATTCAGT TCAGATTTTG ACAGTGGGAT 660
CAGTGCAGCA GAGCGAGAAG ATGGAAATGC GTACTTAGTA AGTAGTGTAT TGATGCGTTT 720
TGATGCAGTT AGGAGGCGGC TCAGCCAAGT AGAATTCACA AAGTCCGCTA CTTCTAAAGC 780
AGCAGGTACT CTGATGAGCA ATGGGGTGCG GACAAACATG AAGAAGAGAG TTGGGACGGT 840
TCCTGGAATT GAGGTTGGAG ATATCTTCTT TTCCCGGATA GAGATGTGTT TAGTGGGTCT 900
TCACATGCAG ACTATGGCTG GCATTGACTA TATAATTAGT AAGGCCGGTT CAGATGAAGA 960
GTCTTTAGCA ACTAGCATTG TTTCATCTGG ACGTTATGAA GGTGAAGCTC AGGATCCTGA 1020
GTCATTAATT TACAGTGGAC AAGGCGGCAA TGCAGACAAG AACAGACAAG CATCTGATCA 1080
GAAGCTTGAA AGGGGTAATC TAGCATTAGA GAATAGCTTG AGGAAGGGAA ATGGAGTAAG 1140
AGTCGTAAGA GGGGAGGAGG ATGCAGCTTC GAAAACAGGA AAGATCTATA TCTATGATGG 1200
GCTTTATTCG ATCTCAGAGT CATGGGTAGA GAAAGGGAAA TCTGGTTGCA ACACCTTTAA 1260
ATATAAATTG GTGAGACAAC CTGGTCAACC ACCTGCGTTT GGCTTTTGGA AATCTGTTCA 1320
GAAGTGGAAG GAAGGTTTGA CTACAAGACC AGGCCTGATC CTTCCAGATC TCACCTCAGG 1380
AGCTGAAAGT AAACCTGTTT CACTTGTGAA TGATGTTGAT GAGGATAAAG GGCCTGCTTA 1440
TTTTACCTAT ACCTCCTCTC TGAAATACTC AGAGACCTTT AAACTAACTC AGCCTGTAAT 1500
TGGTTGTTCC TGCAGTGGTT CATGTTCACC AGGAAATCAT AACTGCTCTT GTATCAGAAA 1560
AAATGATGGT GATCTCCCTT ACCTTAATGG GGTTATACTC GTTTCCCGGA GGCCTGTGAT 1620
ATATGAATGT GGCCCAACGT GTCCTTGTCA TGCCAGTTGC AAAAACAGAG TGATTCAGAC 1680
AGGACTGAAA TCCCGCCTGG AAGTGTTTAA GACAAGAAAC CGCGGTTGGG GTTTACGTTC 1740
GTGGGATTCC TTACGTGCTG GTTCTTTCAT ATGTGAATAT GCTGGTGAAG TCAAAGACAA 1800
TGGCAACCTT AGAGGAAACC AAGAAGAGGA TGCGTATGTC TTTGACACAT CGCGTGTTTT 1860
TAACTCGTTT AAGTGGAATT ATGAGCCTGA GCTTGTAGAT GAAGACCCTT CAACTGAAGT 1920
TCCCGAAGAG TTTAATCTCC CATCACCACT CCTAATCAGT GCCAAGAAAT TTGGCAATGT 1980
AGCTCGGTTC ATGAACCATA GTTGCTCTCC TAACGTTTTT TGGCAGCCAG TTATTCGTGA 2040
AGGAAACGGT GAATCAGTTA TCCACATTGC TTTCTTTGCC ATGCGTCATA TCCCTCCTAT 2100
GGCAGAATTG ACATATGATT ATGGGATTTC TCCTACATCC GAGGCCAGAG ATGAGAGCCT 2160
TTTACATGGA CAGAGGACAT GTCTCTGTGG ATCTGAGCAA TGTCGTGGTT CATTCGGATG 2220
ATCTGAGAGT TTGAGACTGT TTATCTAATT AACACAATCC GTTTGAAACC ATTTATATTG 2280
TCACAGGACA GAAAGTATGT GTGTAGCAGA GTAAGTGGTG GCTTTTGTTC TTCTTCTTAA 2340
CGTAATAGTG GTTGCCGTTT TTGAAAACTG TGTATTGTTA TGTGAATGCA TACACATCTA 2400
ATATATTGTT TATGTATTAG CACC 2425
Sequence Source Ensembl
Keyword

KW-0137--Centromere
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
--
Interpro

IPR025794--Hist-Lys_N-MeTrfase_plant
IPR003616--Post-SET_dom
IPR007728--Pre-SET_dom
IPR015947--PUA-like_domain
IPR001214--SET_dom
IPR003105--SRA_YDG
PROSITE

PS50868--POST_SET
PS50867--PRE_SET
PS51575--SAM_MT43_SUVAR39_2
PS50280--SET
PS51015--YDG
Pfam

PF05033--Pre-SET
PF02182--SAD_SRA
PF00856--SET
Gene Ontology

GO:0005694--C:chromosome
GO:0000775--C:chromosome, centromeric region
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0042054--F:histone methyltransferase activity
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0040029--P:regulation of gene expression, epigenetic
Orthology
WERAM ID Ensembl Protein ID Species Identity E-value Score
WERAM-Arl-0122 scaffold_202240.1 Arabidopsis lyrata 93 0.0 1181
WERAM-Bro-0112 Bo6g088080.1 Brassica oleracea 80 0.0 993
WERAM-Brr-0081 Bra016018.1-P Brassica rapa 77 0.0 982
WERAM-Pot-0004 POPTR_0001s07390.1 Populus trichocarpa 58 0.0 721
WERAM-Thc-0121 EOY19472 Theobroma cacao 58 0.0 712
WERAM-Viv-0081 VIT_13s0047g00120.t01 Vitis vinifera 54 0.0 680
WERAM-Prp-0040 EMJ05444 Prunus persica 52 0.0 658
WERAM-Glm-0034 GLYMA04G15120.1 Glycine max 50 0.0 632
WERAM-Met-0060 KEH32911 Medicago truncatula 49 4e-180 629
WERAM-Sot-0091 PGSC0003DMT400077329 Solanum tuberosum 47 8e-156 548
WERAM-Sol-0115 Solyc09g082050.2.1 Solanum lycopersicum 47 2e-155 546
WERAM-Zem-0004 AC233961.1_FGP001 Zea mays 53 8e-152 535
WERAM-Orp-0070 OPUNC07G07250.1 Oryza punctata 53 2e-151 533
WERAM-Org-0110 ORGLA11G0160500.1 Oryza glaberrima 53 2e-151 533
WERAM-Orb-0118 OBART11G19080.1 Oryza barthii 53 2e-151 533
WERAM-Ors-0105 OS11T0602200-01 Oryza sativa 53 2e-151 533
WERAM-Orr-0118 ORUFI11G20440.1 Oryza rufipogon 53 2e-151 533
WERAM-Brd-0100 BRADI4G25940.1 Brachypodium distachyon 45 2e-151 533
WERAM-Orl-0082 KN539783.1_FGP008 Oryza longistaminata 53 3e-151 533
WERAM-Sob-0019 Sb02g006620.1 Sorghum bicolor 53 3e-151 533
WERAM-Sei-0106 Si028938m Setaria italica 53 5e-151 532
WERAM-Orbr-0036 OB0348G10010.1 Oryza brachyantha 54 1e-150 531
WERAM-Orni-0117 ONIVA11G18710.1 Oryza nivara 53 2e-150 530
WERAM-Orgl-0113 OGLUM11G18450.2 Oryza glumaepatula 53 8e-149 525
WERAM-Tra-0156 Traes_4DL_7DA2A133B.1 Triticum aestivum 53 1e-148 524
WERAM-Hov-0083 MLOC_63544.1 Hordeum vulgare 53 2e-148 523
WERAM-Lep-0057 LPERR05G16930.1 Leersia perrieri 52 9e-146 514
WERAM-Orm-0054 OMERI05G19070.1 Oryza meridionalis 51 2e-145 513
WERAM-Aet-0062 EMT00374 Aegilops tauschii 43 1e-143 508
WERAM-Ori-0115 BGIOSGA033726-PA Oryza indica 54 1e-143 507
WERAM-Tru-0049 TRIUR3_21530-P1 Triticum urartu 42 3e-139 493
WERAM-Amt-0085 ERM98215 Amborella trichopoda 47 7e-121 432
WERAM-Sem-0004 EFJ22703 Selaginella moellendorffii 40 1e-92 338
WERAM-Php-0129 PP1S9_150V6.1 Physcomitrella patens 41 3e-83 307
Created Date 25-Jun-2016