Erinaceus europaeus      Me_Reader      PHD

※ PHD family introduction

    PHD: Distinct from the Royal family is the PHD finger, a well-characterized reader of H3K4me3. It contains a C4HC3 motif that coordinates two zinc ions in a cross-brace manner. Such an arrangement produces a globular domain with a small β-sheet and an α-helix. PHD fingers make extensive contacts with H3K4me3, imparting a high degree of specificity. (1)

Reference
1. Musselman CA, Lalonde ME, Cote J, Kutateladze TG.Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol.2012;19(12):1218-27. PMID: 23211769.



There are 29 genes.  Reviewed (0 or Unreviewed (29

No.StatusWERAM IDGene/Alias Name
1
WERAM-Ere-0003
BAZ1A
2
WERAM-Ere-0004
BRPF1
3
WERAM-Ere-0007
UHRF1
4
WERAM-Ere-0009
KAT6A
5
WERAM-Ere-0012
KDM5B
6
WERAM-Ere-0017
BAZ1B
7
WERAM-Ere-0020
BRD1
8
WERAM-Ere-0023
PHF14
9
WERAM-Ere-0035
TAF3
10
WERAM-Ere-0040
PHF13
11
WERAM-Ere-0043
ING2
12
WERAM-Ere-0048
KAT6B
13
WERAM-Ere-0080
KMT2D
14
WERAM-Ere-0083
PHF20
15
WERAM-Ere-0088
PHF3
16
WERAM-Ere-0098
KDM5A
17
WERAM-Ere-0099
DIDO1
18
WERAM-Ere-0102
CHD4
19
WERAM-Ere-0103
TRIM24
20
WERAM-Ere-0104
BPTF
21
WERAM-Ere-0106
KMT2E
22
WERAM-Ere-0108
JADE1
23
WERAM-Ere-0110
ING4
24
WERAM-Ere-0114
KDM5C
25
WERAM-Ere-0115
KMT2B
26
WERAM-Ere-0120
PHF10
27
WERAM-Ere-0126
PHF12
28
WERAM-Ere-0129
WHSC1
29
WERAM-Ere-0132
CHD3