Homo sapiens      HMT      RIZ

※ RIZ family introduction

    RIZ: RIZ is an Rb-binding protein and also a co-activator of the oestrogen receptor. It contains an N-terminal SET domain and a C-terminal domain that allows RIZ proteins to dimerize. The RIZ SET domain has previously been referred to as a PR-domain. To date, none of the RIZ proteins has been shown to possess methyltransferase activity, probably because of inappropriate assay conditions. (1)

Reference
1. Schneider R, Bannister AJ, Kouzarides T.Unsafe SETs: histone lysine methyltransferases and cancer. Trends Biochem Sci.2002;27(8):396-402. PMID: 12151224.



There are 9 genes.  Reviewed (7 or Unreviewed (2

No.StatusWERAM IDGene/Alias Name
1
WERAM-Hos-0020
PRDM1; BLIMP1; PRDI-BF1
2
WERAM-Hos-0094
PRDM2; RIZ; KMT8; RIZ1; RIZ2; MTB-ZF; HUMHOXY1
3
WERAM-Hos-0119
PRDM12; PFM9
4
WERAM-Hos-0133
PRDM5; BCS2; PFM2
5
WERAM-Hos-0142
PRDM16; MEL1; LVNC8; PFM13; CMD1LL
6
WERAM-Hos-0160
PRDM8; PFM5
7
WERAM-Hos-0177
PRDM9; PFM6; MSBP3; ZNF899; MEISETZ
8
WERAM-Hos-0042
MECOM
9
WERAM-Hos-0112
PRDM7